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Cialis is a medication that helps men who experience erectile difficulties overcome their sexual problems and enjoy an improved self-confidence through better and longer erections. The formula of Cialis includes Tadalafil, which is a PDE5 inhibitor drug that has a similar chemical composition as Viagra (Sildenafil) or Avanafil. Cialis is unique among other representatives of drugs used to relieve the signs and symptoms of erectile dysfunction. Although the manner in which Tadalafil works on a cellular and biochemical level are similar and closely related to the way Viagra works, the time of positive, beneficial action in terms of facilitating erections in men is what differs substantially. While Sildenafil works for about 3 hours after it has been ingested, Tadalafil is able to sustain its action for up to 2 days. Medical research studies that evaluated the pharmaceutical properties of Cialis concluded that the drug is able to work in the interval between 36 and 48 hours, depending on each man's metabolism and drug elimination characteristics. Moreover, it appears that Cialis (Tadalafil) is able to start working faster than other similar remedies for ED belonging to the class of PDE5 inhibitors. This unique biochemical profile of Cialis has earned it the name of "the weekend pill", and the drug is associated with an increasing popularity among male users who are looking to improve their sexual performance and enjoy the full benefits of a normal sexual lifestyle. Cialis is designed to replicate the huge popularity of Viagra, and even enhance it through its unique properties and effective action.
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How does Cialis work to achieve the enhancement of erections in men who struggle with ED problems?

Tadalafil, which is included in the formula of Cialis pills, is known to inhibit the PDE5 enzyme, and thus plays a huge role in addressing the physiologic deficiences at the biochemical level. Sexual arousal occurs in the brain, and it is accompanied by a signal that travels to the nerve endings in the penis. The nerves are activated through the release of nitric oxide (NO), which is produced to influence the enzyme that generates cyclic GMP. This active compound (cGMP) has the role to influence the blood vessels to become wider, a process called blood vessel dilation, which results in a huge amount of blood being diverted into the cavernous chambers located in the penis. The erection is essentially the process of receiving an increasing volume of blood into the penis, which is achieved through the effective action of cyclic GMP on the blood vessels. However, cGMP is not available to work for a long period of time because of the existence of PDE5 enzyme, which destroys it relatively quickly. In some men, this mechanism coupled with a psychological problem linked to a low self-confidence may translate into erectile problems and deficiencies in their sex life. Cialis was designed to act as a blocker for the PDE5 enzyme located in the penis, which translates into increasing quantities of cGMP remaining available for erection-stimulating effects. Cialis is traditionally formulated as pills that are ingested, and which start their work in about 30 minutes after their intake. The drug is effective for about two days, which means that you can experience erections and sexual intercourse anytime you are sexually aroused with your partner.

Although Cialis is a safe remedy for ED, it may cause minor and rapidly diminishing side effects in rare cases. Make sure to undergo an assessment by your physician if you exhibit signs such as persistent headaches, abdominal pain, sensitivity to excessive light or a stuffy nose. These may represent minor unwanted effects of Cialis, but they occur only in a minority of patients who take it. Be sure not to exceed the prescribed dosage and to monitor closely the intervals between Cialis administrations. Cialis is usually prescribed for patient who have ED, but occassionally may help individuals afflicted by pulmonary hypertension, depending on their doctor's recommendations.

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